LDL is produced first as a precursor particle, very low density lipoprotein (VLDL). VLDL carries a large core of triglyceride. While in the circulation, the triglyceride is hydrolyzed by lipoprotein lipase, an enzyme that resides on the luminal surface of the capillary endothelium of cells that will either store (adipocytes) or oxidize (muscle) the fatty acids that are released by the lipolysis reaction. Upon depletion of most of its triglyceride core, the remaining particle becomes LDL. Thus, through selective removal of its triglyceride core, a triglyceride-rich lipoprotein becomes a cholesterol-rich lipoprotein.
3 comments:
Mmmmm...Ok.
Give Nilz some donuts please!
(K)
that's your job, my dear :o
I can't remember which is the good cholesterol, LDL or HDL. In any case, I have high cholesterol, probably from eating too many donuts. ;-)
P.S. Biochemistry is sooo interesting.
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